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Scientific Programme
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Friday, September 24, 201016.00 – 19.00 Registration
Saturday, September 25, 2010
Introduction
| 08:30 |
Welcome
Cihan Yurdaydin, Turkey |
| 08:45 |
Welcome from EASL Secretary General
Heiner Wedemeyer, Germany |
| 08:45-09:15 |
Special Lecture: The Delta Virus: From its Discovery to Today
Mario Rizzetto, Italy |
09:15-10:15 |
Session 1: Virology 1
Chairs: John Gerin, USA and A. Mithat Bozday, Turkey |
| 09:15 |
Delta Virus and Viroids: Similarities and Differences
Ricardo Flores, Spain |
| 09:40 |
Discussion |
| 09:45-10:10 |
Structure and Replication of HDV
John Taylor, USA |
| 10:10 |
Discussion |
| 10:15-10:45 |
Coffee Break / Poster Viewing |
10:45-12:15 |
Session 2: Virology 2
Chairs: Mario Rizzetto, Italy and John Taylor, USA |
| 10:45 |
HBV – HDV interaction: Guides for a Successful Marriage
Camille Sureau, France |
| 11:10 |
Discussion |
| 11:15 |
Hepatitis Delta Antigen-biochemical and Functional Properties
Pei-Jer Chen, Taiwan |
| 11:40 |
Discussion |
| 11:45 |
Life Cycle and Potential Therapeutic Targets
Jeffrey Glenn, USA |
| 12:10 |
Discussion |
| 12:15-14:00 |
Lunch Break / Poster Viewing |
14:00-15:40 |
Session 3: Pathogenesis
Chairs: Michael P. Manns, Germany and Georgios Dalekos, Greece |
| 14:00 |
Animal and In Vitro Models of Delta Depatitis
Michael Roggendorf, Germany |
| 14:20 |
Discussion |
| 14:25 |
Immunopathogensis of Delta Hepatitis
Heiner Wedemeyer, Germany |
| 14:45 |
Discussion |
| 14:50 |
Triple and Quadriple Infection
Vincent Sorriano, Spain |
| 15:10 |
Discussion |
15:15-16:15 |
Presentation of Selected Abstracts
Chairs: Giovanni Gaeta, Italy and Heiner Wedemeyer, Germany |
| 15:15 - 15:27 |
The Ispoprenylated Large Isoform of Hepatitis Delta Virus Protein Activates STAT-3 and NF-κB, via Oxidative Stress: plus discussion
Segolene Brichler, France |
| 15:27 - 15:39 |
Study of the Replication of Hepatitis Delta Virus (HDV) CLADE 1, 6 and 8 Prototypes in Cell Culture: plus discussion
Vannary Mom, France |
| 15:39 - 15:51 |
Human Liver Chimeric uPA Mice as a New Animal Model for the Study of HDV/HBV Infection: plus discussion
Lida Mancke, Germany |
| 15:51 - 16:03 |
Protection of Woodchucks From Hepatitis D Virus Infection After Immunization With DNA Immunization and Adenoviral Boost: plus discussion
Melanie Fiedler, Germany |
| 16:03 - 16:15 |
Intrahepatic HDV RNA, HBV DNA and HBV RNAs Quantifications Reveal Suppression of HBV Pregenome RNA Production with Maintenance of preS/S Transcription in HDV/HBV Co-infected Patients: plus discussion
Teresa Pollicino, Italy |
| 16:15-16:45 |
Coffee Break / Poster Viewing |
16:45-18:30 |
Session 4: Epidemiology
Chairs: Stephanos Hadziyannis, Greece and Ramazan Idilman, Turkey |
| 16:45 |
Turkey
Halil Degertekin, Turkey |
| 17:00 |
Europe
Emmanuel Manesis, Greece |
| 17:15 |
The Americas
Raimundo Parana, Brazil |
| 17:30 |
Asia
Jaw-Ching Wu, Taiwan |
17:45-18:30 |
Roundtable Discussions on Epidemiology
Chairs: Mario Rizzetto, Italy, Emmanuel Manesis, Greece
Raimundo Parana, Brazil, Jaw-Ching Wu, Taiwan |
18:30 |
Conference Reception |
Sunday, September 26, 2010
08:30-10:35 |
Session 5: Diagnosis and Natural History
Chairs: Nurdan Tözün, Turkey and Patrizia Farci, Italy |
| 08:30 |
Diagnosis of HDV Infection: Need for Standardization
Jean-Michel Pawlotsky, France |
| 08:50 |
Discussion |
| 08:55 |
Histopathology of Delta Hepatitis
Hans P. Dienes, Germany |
| 09:15 |
Discussion |
| 09:20 |
HDV Genotypes
Emmanuel Gordien, France |
| 09:40 |
Discussion |
| 09:45 |
Natural History of CDH
Cihan Yurdaydin, Turkey |
| 10:05 |
Discussion |
| 10:10 |
HDV Infection and Hepatocellular Carcinoma
Massimo Colombo, Italy |
| 10:30 |
Discussion |
| 10:35-11:00 |
Coffee Break / Poster Viewing |
11:00-13:05 |
Session 6: Treatment
Chairs: Maria Buti, Spain and Hakan Bozkaya, Turkey |
| 11:00 |
Treatment of Delta Hepatitis with Interferons
Patrizia Farci, USA |
| 11:20 |
Discussion |
| 11:25 |
Combination Treatment in Delta Hepatitis
Ulus S. Akarca, Turkey |
| 11:45 |
Discussion |
| 11:50 |
A Role for Nucleos(t)ide Analogs in HDV Treatment?
Grazia A. Niro, Italy |
| 12:10 |
Discussion |
| 12:15 |
Liver Transplantation in Delta Hepatitis
Didier Samuel, France |
| 12:35 |
Discussion |
| 12:40 |
Novel Treatment Options for Delta Hepatitis
Stephan Urban, Germany |
| 13:00 |
Discussion |
| 13:05-14:15 |
Lunch Break / Poster Viewing |
14:15-16:00 |
Session 7: The Future - Panel
Chairs: Michael P. Manns, Germany and Jeffrey Glen, USA |
| 14:15 |
Unmet Needs in Delta Hepatitis
Michael P. Manns, Germany |
| 14:45 |
Towards Standardization of HDV RNA Measurement
Michael Chudy, Germany |
15:05 |
Roundtable Discussion: Delta Hepatitis Research - Missing Areas
Clinical vs. Basic - Panel
Clinical: Mario Rizzetto, Michael P. Manns, Heiner Wedemeyer, Jaw-Ching Wu, Cihan Yurdaydin
Basic: John Gerin, John Taylor, Stephan Urban, Jeffrey Glenn, Pei-Jer Chen, Ricardo Flores |
| 16:05 |
Summary of the Conference
Michael P. Manns, Germany |
| 16:10 |
The Vision of EASL: Final Remarks from the EASL Secretary General
Heiner Wedemeyer, Germany |
| 16:20 |
Closure of Conference |
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