Scientific Programme

THURSDAY, JANUARY 22, 2009

15:00 – 19:00 Registration
16:30 ‑ 16:40

Opening Address
by Conference Organizing Committee -
J. Bosch, Spain, A.K. Burroughs, UK, R. de Franchis, Italy
followed by F. Szalay, Hungary

16:40-18:40

Session I:
Pathobiology of the Vascular Endothelium and Portal Hypertension

Chair: R. Groszmann, New Haven, CT, USA
16:40

Pathobiology of the Vascular Endothelium
W.C. Sessa, New Haven, CT, USA

17:10

Oxidative Stress and Vascular Function
R.P. Brandes
, Frankfurt, Germany

17:40

Regulation of Endothelial Phenotype
G. García-Cardeña, Boston, MA, USA

18:10

Factors modulating e-NOS expression/activity
Y. Iwakiri, New Haven, CT, USA

   

FRIDAY, JANUARY 23, 2009

08:30-10:20

Session II:
Pathobiology of the Vascular Endothelium in Cirrhosis

Chair: W.C. Sessa, New Haven, CT, USA
08:30

Hepatic eNOS in Cirrhosis
V. Shah
, Rochester, MN, USA

09:00

Eicosanoids
J.C. García-Pagán, Barcelona, Spain

09:30

Hydrogen Sulphide
S. Fiorucci, Perugia, Italy

10:00

Tribute to Roberto Groszmann
Presented by: G. García-Tsao, New Haven, CT, USA

10:20 ‑ 10:45 Coffee Break
10:45-16:00

Session III:
Splanchnic Haemodynamics

 

10:45

Chairs: J.C. García-Pagán, Spain, V. Shah, USA

The Hyperkinetic Syndrome
R. Groszmann, New Haven, CT, USA

11:15

Endocannabinoids
G. Kunos, Bethesda, MD, USA

11:45

Lipid Metabolism and Vascular Function
R. Moreau, Clichy, France

12:10

Rho Proteins and Regulation of Vascular Tone in Cirrhosis
M. Hennenberg, Bonn, Germany

12:35

The Role of Bacterial Translocation
A. Albillos, Madrid, Spain

13:00 ‑ 14:30 Lunch Break
14:30

Splanchnic Angiogenesis
M. Fernandez, Barcelona, Spain

15:00

Pharmacological Modification of Splanchnic Blood Flood
P.C. Hayes, Edinburgh, UK

15:30

Pharmacological Modification of Hepatic Vascular Resistance
J. Bosch, Barcelona, Spain

16:00 ‑ 16:30 Coffee Break
16:30-18:30

Session IV:
Structural Changes in Cirrhosis

Chair: J. Bosch, Spain
16:30

Vascular Occlusion and Parenchymal Extinction
IR Wanless, Halifax, Nova Scotia, Canada

17:00

Fibrogenesis
S.L. Friedman, New York, NY, USA

17:30

Angiogenesis and Inflammation
M. Pinzani, Florence, Italy

18:00

Reversibility of Fibrosis
J.P. Iredale, Edinburgh, UK

20:00

Conference Buffet Dinner

   

SATURDAY, JANUARY 24, 2009

08:30-11:05

Session V:
Diagnostic Tests in Portal Hypertension

Chairs: G. D'Amico, Italy, G. García-Tsao, New Haven, CT, USA

08:40

Methodology of Diagnostics Tests
E. Christensen, Copenhagen, Denmark

09:10

Evaluation of Fibrosis and Portal Hypertension:

09:10

I. Histology as a Gold Standard for Assessing Fibrosis/Cirrhosis
M. Guido, Padova, Italy

09:30

II. Endoscopy vs. Capsule Endoscopy in the Diagnosis of Varices
R. de Franchis, Milan, Italy

09:55

III. HVPG as a Gold Standard: How to do it Properly
R. Bañares, Madrid, Spain

10:20

IV. Non-invasive assessment: French Approach
D. Thabut, Paris, France

10:45

V. Non-invasive assessment: U.S.A. Approach
J.A. Talwalkar, Rochester, MN, USA

11:05 ‑ 11:30 Coffee Break
11:30-13:00

Session VI: Prognosis

Chair: A.K. Burroughs, London, UK
11:30

Construction and Validation of Prognosis Models
T.I. Sørensen, Copenhagen, Denmark

12:00

Prognostic Models in Portal Hypertension: Stages of Cirrhosis
G. D’Amico, Palermo, Italy

12:30

HVPG and Prognosis
G. García-Tsao, New Haven, CT, USA

13:00 ‑ 14:30

Lunch Break

14:30-16:30

Session VII:
Treatment: New Evidences Following Baveno 2005
and Atlanta 2007

Chair: R. de Franchis, Italy
14:30

Pre-Primary and Primary Prophylaxis
C. Merkel, Padova, Italy

15:00

Secondary Prophylaxis
D. Lebrec, Clichy, France

15:30

Predictors of Failure to Standard Therapy: HVPG and Beyond
A.K. Burroughs, London, UK

16:00

Advances in the Treatment of Acute Bleeding
J.G. Abraldes, Barcelona, Spain

16:30 ‑ 17:00

Coffee Break

17:00-18:40

Session VIII:
Emerging Therapies for Portal Hypertension

Chair: P.C. Hayes, Edinburgh, UK
17:00

Advances in the Management of BCS and PHPVO
D. Valla, Clichy, France

17:30

New Endoscopic Therapies          
C. Villanueva, Barcelona, Spain

18:00

Radiological Rescue Therapies
J.P. Vinel, Toulouse, France

18:30

Closing Remarks
 J. Bosch, Spain, A.K. Burroughs, UK, R. de Franchis, Italy