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Preliminary Scientific Program
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Friday, February 27, 2009 |
| 15:00 – 19:00 |
Registration |
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General State of the Art Lectures
Chair: Michael Trauner, Graz, Austria |
| 17:00 |
Opening Remarks
Michael Trauner, Graz, Austria |
| 17:10 |
Basic Liver Nuclear Receptor State of the Art Overview
David Moore, Houston, TX, USA |
| 18:00 |
Clinical Perspective State of the Art Overview
Saul J. Karpen, Houston, TX, USA |
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Saturday, February 28, 2009 |
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Fatty Liver and Metabolic Syndrome
Chair: Saul J. Karpen, Houston, TX, USA |
| 08:00 |
Day 2 Remarks
Michael Trauner, Graz, Austria |
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08:05 |
PPARγ and LXRs
Antonio Vidal-Puig, Cambridge, UK |
| 08:35 |
Bile Acid Signaling from Nuclear to Membrane Receptors
Johan Auwerx, Lausanne, Switzerland |
| 09:05 |
Role of SHP for Pathogenesis of Fatty Liver and Hepatocellular Cancer
Li Wang, Salt Lake City, Utah, USA |
| 09:35 ‑ 10:00 |
Coffee Break
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Metabolism / Inflammation / Fibrosis
Chair: Massimo Pinzani, Florence, Italy |
| 10:00 |
PPAR alpha in Alcohol-induced Liver Disease
Frank Gonzalez, Bethesda, MD, USA |
| 10:30 |
Impact of Inflammation on Nuclear Receptor Biology
Micheline Piquette-Miller, Toronto, ON, Canada |
| 11:00 |
Regulation of Metabolism by Nuclear Receptor-FGF Pathways
Steven Kliewer, Dallas, TX, USA |
| 11:30 |
Stellate Cells and Nuclear Receptors
Massimo Pinzani, Florence, Italy |
| 12:00 ‑ 13:00 |
Lunch
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Cholestasis / Drug Metabolism / Cholelithiasis
Chair: Raoul Poupon, Paris, France |
| 13:00 |
Bile Acid Metabolism
John Chiang, Rootstown, OH, USA |
| 13:30 |
Adaptation to Cholestasis
Gernot Zollner, Graz, Austria |
| 14:00 |
FXR and Liver Disease / Cholestasis / Cholelithiasis
Antonio Moschetta, Bari, Italy |
| 14:30 |
Nuclear Receptors and Hepatoxicity
Gerd Kullak-Ublick, Zurich, Switzerland |
| 15:00 - 15:30 |
Coffee Break |
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Metabolism/ Genetics
Chair: Frank Lammert, Homburg, Germany |
| 15:30 |
Antidiabetic effects of LRH-1 activation
David Moore, Houston, TX, USA |
| 16:00 |
Transporter and Nuclear Receptor Polymorphisms and Liver Disease
Frank Lammert, Homburg, Germany |
| 16:30 |
Nuclear Receptor Polymorphisms in Humans
Erin Schuetz, Memphis, TN, USA |
| 17:00 |
Oral Presentation |
| 17:15 |
Poster Viewing |
| 19:30 |
Conference Buffet Dinner |
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Sunday, March 1, 2009 |
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Nuclear Receptor Ligands and New Applications
Chair: Richard A. Heyman, San Diego, CA, USA |
| 08:00 |
Day 3 Remarks
Saul J. Karpen, Houston, TX, USA |
| 08:05 |
Drug Design
Hinrich Gronemeyer, Illkirch/Strassburg, France |
| 08:35 |
Selective Nuclear Receptor Regulators
Richard A. Heyman, San Diego, CA, USA |
| 09:05 |
Estrogen Receptors and Cholangiopathies
Domenico Alvaro, Rome, Italy |
| 09:35 |
Role of FXR in replication of hepatitis viruses
Patrice Andre, Lyon, France |
| 10:05 - 10:45 |
Coffee Break |
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Clinical Trials, Present and Future Treatments
Chair: Ulrich Beuers, Amsterdam, The Netherlands |
| 10:45 |
Nuclear Receptor Clinical Trials in Liver Disease
Keith Lindor, Rochester, MN, USA |
| 11:15 |
Future Proposals and Needs
Michael Trauner, Graz, Austria |
| 11:45 |
Oral Presentation |
| 12:00-12:10 |
Conference Wrap-Up
Saul J. Karpen, Houston, TX, USA |
| 12:10 - 13:30 |
Lunch | |
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